PhD Biomedical Sciences (Tropical Medicine), John A. Burns School of Medicine, University of Hawaii 2013
MS Biomedical Sciences (Tropical Medicine), John A. Burns School of Medicine, University of Hawaii 2009
DVM College of Veterinary Sciences, Mhow, India 2007
Pathogenesis of Infectious Diseases, SARS-COV-2, COVID-19, West Nile Virus, Zika Virus
Mukesh Kumar is a virologist and immunologist with expertise in the studies of RNA virus/host interactions. Kumar’s major area of research interest is to identify novel therapeutic targets and diagnostic biomarkers for emerging infectious diseases, which include COVID-19, West Nile virus encephalitis and Zika virus-associated neurological disease. His research involves studying how SARS-CoV-2, causative agent of COVID-19, is transmitted in animals in order to better understand how the virus spreads and how it takes hold in the body. His lab is studying the pathogenic mechanisms underlying the development of lung and kidney malfunctions during SARS-COV-2 infection. The goal is to develop therapeutic strategies to ameliorate SARS-COV-2-associated disease pathology and prevent the disease transmission.
Lab Telephone: (404) 413-5334 / (404) 413-5373
Lab Location: 534/589 Petit Science Center (PSC)
Lab Members Position Hussin Rothan Post-Doctoral Fellow email@example.com Philip Strate Graduate Student firstname.lastname@example.org Janhavi Prasad Natekar Graduate Student email@example.com Shannon Stone Graduate Student firstname.lastname@example.org Heather Pathak Graduate Student email@example.com
Natekar JP, Rothan HA, Arora K, Strate PG, Kumar M. Cellular microRNA-155 Regulates Virus-Induced Inflammatory Response and Protects against Lethal West Nile Virus Infection. (https://www.ncbi.nlm.nih.gov/pubmed/31861621/) Viruses. 2019 Dec 19; 12 (1). doi: 10.3390/v12010009. PubMed PMID: 31861621.
Rothan HA, Kumar M. Role of Endoplasmic Reticulum-Associated Proteins in Flavivirus Replication and Assembly Complexes. (https://www.ncbi.nlm.nih.gov/pubmed/31547236/) Pathogens. 2019 Sep 12; (3). doi: 10.3390/pathogens8030148. Review. PubMed PMID: 31547236 ; PubMed Central PMCID: PMC6789530.
Rothan HA, Arora K, Natekar JP, Strate PG, Brinton MA, Kumar M. Z-DNA-Binding Protein 1 Is Critical for Controlling Virus Replication and Survival in West Nile Virus Encephalitis. (https://www.ncbi.nlm.nih.gov/pubmed/31572318/) Front Microbiol. 2019; 10 :2089. doi: 10.3389/fmicb.2019.02089. eCollection 2019. PubMed PMID: 31572318 ; PubMed Central PMCID: PMC6749019.
Azouz F, Arora K, Krause K, Nerurkar VR, Kumar M. Integrated MicroRNA and mRNA Profiling in Zika Virus-Infected Neurons. (https://www.ncbi.nlm.nih.gov/pubmed/30781519/) Viruses. 2019 Feb 16; 11 (2). doi: 10.3390/v11020162. PubMed PMID: 30781519 ; PubMed Central PMCID: PMC6410042.
Krause K, Azouz F, Nakano E, Nerurkar VR, Kumar M. Deletion of Pregnancy Zone Protein and Murinoglobulin-1 Restricts the Pathogenesis of West Nile Virus Infection in Mice. (https://www.ncbi.nlm.nih.gov/pubmed/30814992/) Front Microbiol. 2019; 10 :259. doi: 10.3389/fmicb.2019.00259. eCollection 2019. PubMed PMID: 30814992 ; PubMed Central PMCID: PMC6381297.